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What is happening with H7N9 in China?

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Based on illness onset dates from January through the end of November 2016, China officially reported about 115 human cases H7N9 infection. Over the course of several days in early January 2017, China notified the World Health Organization of more than 100 additional human cases of H7N9 presumably having been infected in December 2016. It appears that almost as many people were infected in December as all of the preceding months in 2016. The graph below shows the distribution of H7N9 cases by onset date where available and then by reporting date. The graph clearly shows the large increases in the number of infected individual reported recently. Should this increase be a cause for alarm? Increases in human cases of avian influenza always increase the risk for sustained human to human transmission of the disease. Reviewing the minimal data that is available for the 107 recent cases reported by China, some observations can be made. About 36% of these new cases are female and 67% are male...

A Review of Human Influenza A(H7N9) Infections in 2016

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Note: Between January 1 and January 9 2017, China officially reported  to WHO at least another 107 human cases of H7N9 most with onset dates in 2016. The information presented below relates to  the first 125 cases reported with onset dates in 2016.  updated January 11, 2017 The first officially reported human case of infection from a reassortant avian influenza A(H7N9) virus was from the People’s Republic of China (China) in March of 2013, although human H7N9 infection may have occurred in or near Hong Kong as early as 2007 (FAO ID event 220957). Since 2013 the World Health Organization (WHO) has officially reported 808 human cases of H7N9 as of December 23, 2016. In the past few days, an additional 13 H7N9 cases have been reported by public health officials in China but have not yet been published by the WHO. Of these 821 cases, 696 have onset or reporting dates prior to December 31, 2015. The total number of reported H7N9 cases in 2016 is 125. Geographic Distribution ...

MERS is Widespread in Saudi Arabia

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Middle East Respiratory Syndrome (MERS) has infected at least 1370 individuals (including asymptomatic cases) in Saudi Arabia since 2012 ( e.g. ProMED link ). Since mid-February 2016, Buraidah in Al Qassim region in Saudia Arabia has been experiencing a local MERS outbreak with 23 cases reported through March 16, 2016 ( link ). As of April 3, 2016 there have been an additional 11 cases reported, bringing the total cases reported from Buraidah by Saudi Arabia Ministry of Health to 34.   Many of these cases are a result of nosocomial infection, but perhaps as many as eight of these cases were community acquired infections with some individuals having contact with animals. Among these 34 cases, 17 have been reported as deaths so far. (see note) While the Buraidah MERS outbreak has raised concerns, the 34 cases from Buraidah represented about 40% of all MERS cases reported from Saudi Arabia since January 1, 2016. The majority of MERS cases since January 1, 2016, about 49 cases, have b...

The MERS Outbreak in Buraidah, Saudi Arabia, February - March 2016

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Since late February, a Middle East Respiratory Syndrome (MERS) outbreak has been occurring in northcentral Saudi Arabia in Buraidah in the Al Qassim region. Through March 16, 2016, there have been 23 MERS cases reported from Buraidah by the Saudi Arabia Ministry of Health (SAMOH), include 6 females and 17 males, ranging in age from 22 to 84 years. Six of the cases are healthcare workers. Based on reports by the SAMOH, 11 of these individuals have died. Only five individuals have been reported to have recovered. Constructing a preliminary timeline of Buraidah outbreak Details are only available from the World Health Organization (WHO) for 18 of these cases prior to March 10, 2016. ( link , link ) At least five of the cases reported by WHO appear to be community-acquired infections which suggest that MERS may be wide-spread in the Buraidah community. These individuals include a 40 year-old male (WHO 1670) who experienced symptoms on February 22 and was hospitalized the same day. It is n...

The Geography of MERS

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Since 2012, the World Health Organization (WHO) has been notified of 1626 laboratory-confirmed cases of Middle East Respiratory Virus Syndrome (MERS) as of January 7, 2016 ( link ). These cases have been reported from 26 countries as shown on the map and table below. Cases have been reported from most continents: North America, Africa, Europe, and Asia. No cases have been yet been reported from South America, Australia, or the sparsely inhabited Antarctica. More than 75% of these cases have been reported from Saudi Arabia.  Countries Reporting MERS infections to WHO   Worldwide count of MERS cases   The earliest cases of MERS in 2012 were geographically associated with countries in the Middle East. Numerous cases in Saudi Arabia are reported as “primary cases”, autochthonous cases, which have been infected from local animal hosts. Current research indicates that camel populations on the Arabian Peninsula are a reservoir for this coronavirus, although there may be ot...